Most turmeric research has been found fraudulent.

From Wikipedia:

> Bharat Aggarwal was a cancer researcher at the University of Texas MD Anderson Cancer Center, who as of April 2018 had 19 papers retracted for research fraud.[18][19] Aggarwal's research had focused on potential anti-cancer properties of herbs and spices, particularly curcumin, and according to a March 2016 article in the Houston Chronicle, "attracted national media interest and laid the groundwork for ongoing clinical trials".

Unrelated but Turmeric often contains elevated levels of lead compared to other spices. Source: https://www.cdc.gov/mmwr/volumes/67/wr/pdfs/mm6746a2-H.pdf

Psychoactive drugs have different effects on different people.

For me, caffeine is the drug that does not really do anything (higher doses in the 300mg+ range are definitely noticeable, but mostly by the physical side effects). Nicotine chewing gum produces a short-lasting mild stimulation (and I have to take a 4mg one, even though I am a non-smoker).

I wonder if some people are predisposed to nicotine while others aren't.

I also tried to smoke, felt nothing good. Hot fire stick that dries out my throat for zero benefit. And I mean zero. I'd look at my friend and be like "WTF is the point of this again?"

But it wouldn't surprise me that other people do feel something.

The first time I smoked I felt the same: nothing good. But eventually I got hooked. You become addicted and feel terrible while not on it. Once you're on it, you're good to go for a while again. (I eventually managed to quit.)

I only tried smoking when drunk and the effect was to make me dizzy, like I’d been spinning on a roundabout too fast.

That effect is normal the first time(s) you smoke. It goes away eventually. The alcohol probably made it worse, or more uncomfortable. Either way, good on you for not starting. I succeeded with not starting various times, but did fail eventually. Growing up with a mother who smoked (did quit too though) who's also my main parent did not help.

I tried smoking when drunk, the effect is I feel more alert and less dizzy.

I've done many drugs in past:

Marijuana, cocaine, heroine, vaping, estasy and did it like a month with friends but i don't feel any addiction.

I did feel some effect but never felt addicted.

But i am addicted to peanut butter, the i don't have atleast one spoon i feel very bad whole day.

So, a serious question. Do you need to do something for longer duration (more than a month?) to get addicted to these drugs?

It's because I have been putting nicotine in your peanut butter.

Nicotine is biologically addictive.

I've quit smoking a couple of times. The hardest part is the first few days: I get really irritated and angry, and I know that I would just need one cigarette to feel alright again. After a few days, the effect wears off, and I feel normal again.

In the long run, the hard part is resisting the urge to start smoking again. There is always some situation where it's so tempting to light a cigarette...

[citation needed]

According to https://www.gwern.net/Nicotine, nicotine itself doesn't seem biologically addictive in a significant way. Only when mixed with other substances in tobacco, the addiction potential manifests itself.

You just don't respond the way that most people do to nicotine. Not every body and brain responds the same way to drugs.