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Re:Deformities Alarm Scientists Racing to Rewrite Animal DNA by hyperpallium on Saturday December 22, 2018 @08:45PM (#18743838)
But will they do worse than random mutation?

Evolution is like Motie Engineers (https://wikipedia.org/wiki/The_Mote_in_God's_Eye). I would summarise the essential difficulty as non-heirarchical.

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