Not yet, though I'm keeping my eye on WASM and will pursue it if the need arises. The sort of work I do has relatively little overhead from the JS, and is mostly bottlenecked by rendering (SVG, mostly). WASM wouldn't help my load/parse times since I rarely ship more than a few Kb of JS, and it wouldn't help my per-frame times or latency because I'm usually done the JS part of the frame in around 1ms.