Serif products (Affinity) have been on a roll, last I checked.

I switched to Affinity and never looked back at Photoshop/Illustrator. That being said, I used them at a hobbyist level, nothing very complex, so while it was an easy transition for me, it may not be for everyone. But I've seen quite a few people state they have moved off of Adobe products over to Serif. I've been very happy with Affinity Photo and Affinity Designer.

Affinity products are fine and fast and stable, but there are many things they don't do. Tracing for example: Corel Draw does tracing beautifully.

They now just released Affinity Publisher in Beta as a replacement for Adobe InDesign. Already using it and very pleased!

Pixelmator still great, as is OmniGraffle (a better Visio) for vector diagrams and my vector-image pirposes.

https://www.pixelmator.com/pro/

https://www.omnigroup.com/

Corel Draw is similar to Adobe Illustrator, not Photoshop

Sketch for UI/UX design.