I do not know of a testosterone formulation approved for IV or nasal. Only for IM which is into the muscle before absorption. Some doctors will allow Sub-Q (in the fat) because several studies have showed it also gets absorbed in fat but at a different rate.

Shrinkage is not as bad as you would think, in my case maybe 25%. However, my doctor also prescribes HCG to be injected IM bi-weekly. HCG is an analog to LH - the signaling hormone that tells the testes to produce testosterone. As a result mine are still producing a little bit of test to keep their size and prevent atrophy (I am still fertile as a result).

Acne pops up when dosage is going up or down but tends to go away if you maintain a stable dose and blood level concentrations (aka dose timing) for a long period of time.

Most people in my family suffer from depression, and I have in the past. I think most of mine was caused by anxiety though. SSRIs when I was a teen never did anything for me. I now am fine with no drugs for it though. If yours is based in anxiety I strongly believe it will help.

I would second the HCG (or similar, clomid?) for anyone that wants to prevent atrophy by keeping your LH levels up. From a medical perspective I would be curious if you could play with HCG or similar by itself to cause your natural T levels to rise without having to take T.

As an anecdotal single data point of how far you can go after keeping my LH levels as low as I could after around eight months straight my testes decreased around 75% in volume.

This is really interesting. Previously, I asked my doctor to try it, and my first dose of the T Pill sent me into a panic attack and scared me from it.

Same history with family and SRRI use.

> What's the advantage of IV over oral / nasal ingestion?

Generally, oral anabolic steroids are more hepatoxic than their IV counterparts. So the advantage is that you end up with less liver damage.

Didn’t realize that TRT is a form of “taking steroids”. Makes sense in hindsight.