I just started working remote - I have a separate office, but it's not 100% for work (I have a 3D printer and other fun distractions in the room). I was a bit concerned at first with having a clear separation and that it being a "work" space would ruin it's appeal during off hours, or I'd be tempted to play when I should be working. I found that not to be a concern by only doing work on my work computer and only doing everything else (except personal email and light browsing) on my personal computer. I have a docking station and plug in one or the other to set my context. This seems to work well, but only time will tell if it's sustainable for me.