Do you think humans would stop at the first hurdle they encounter in their endeavours? How about the 99th hurdle? CRISPR is a naturally occurring gene editing tool. We have only recently started engineering solutions using it. Once this tool meets the full might of human ingenuity and our constant resolve to improve things, it can overcome great biological challenges. Eliminating disease carrying pests, curing genetic defects in children, shortened crop cycles, tastier strawberries these are some amazing possibilities that CRISPR holds. It might take some time but we will get there. So no the game is not over. It won't be over as long as we have a few humans on the case.