Not sure I follow exactly what you're asking. You can do read replicas for HA/failover/read sharding which you can do with regular PostgreSQL databases as well. So at least on the axis TimescaleDB presents no limitations.

Alright thanks! I thought I read that TimescaleDB doesn't support clustering yet, only single node Postgres installs, But I could've misunderstood it.

It does not support sharding writes across multiple nodes, but we do work with streaming replication so you can set up read replicas (and for failover).