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Re:Drug cocktail almost doubles lifespan of worms by cgh on Monday October 29, 2018 @12:40PM (#18328872)
You can also eat a very low-carb diet. Restricting your carbs to foods like greens and berries will have the same effect without the need for a prescription. Gluconeogenesis is demand-driven.

Of course, in the context of anti-aging, Metformin may have other beneficial effects outside of moderating glucose levels.

Re:Drug cocktail almost doubles lifespan of worms by onetimemanytime on Monday October 29, 2018 @02:50PM (#18330123)
Yeah, but taking a pill and eating what you want (more or less) is much better
Re:Drug cocktail almost doubles lifespan of worms by village-idiot on Monday October 29, 2018 @12:54PM (#18328983)
Fasting is also a good idea. It forces your body to kill off marginal cells for food, rather than leaving them to potentially become cancer.
Re:Drug cocktail almost doubles lifespan of worms by _Schizotypy on Monday October 29, 2018 @01:07PM (#18329095)
Can you cite a source please? I would be very interested in reading it
Re:Drug cocktail almost doubles lifespan of worms by sushid on Monday October 29, 2018 @02:03PM (#18329628)
Not the parent but try searching online for fasting and autophagy. There are countless sources regarding this link.

Another good recent study is the intestinal stem cell regenerative boost after a 24 hour fast in mice.

One might say that the links are still not solid, but we do know that lowering glucose levels might be a good idea (hence the interest in metformin) and fasting/keto certainly achieves that without a drug.

Re:Drug cocktail almost doubles lifespan of worms by village-idiot on Monday October 29, 2018 @05:50PM (#18331858)
I really like the stuff that Mark Sisson writes on fasting[0], because he explains and links all his sources.

0. https://www.marksdailyapple.com/health-benefits-of-intermitt...

Re:Drug cocktail almost doubles lifespan of worms by BurningFrog on Monday October 29, 2018 @11:50PM (#18333898)
Oh, that's a cute concrete theory I've never heard before.

I do fast occasionally, but not as often as I'd wish.

Re:Drug cocktail almost doubles lifespan of worms by village-idiot on Tuesday October 30, 2018 @08:33AM (#18335892)
If you want to learn more, the biological process is called “autophagy”.