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Re:Responder: A familiar HTTP Service Framework by jklehm on Tuesday October 16, 2018 @10:49PM (#18235745)
If you can manage with Flask there's Quart [1]

[1] https://gitlab.com/pgjones/quart

Re:Responder: A familiar HTTP Service Framework by bpicolo on Wednesday October 17, 2018 @08:59AM (#18238493)
I've been using quart for some projects recently. Was super easy to move to from flask (though had to upstream a couple compat fixes). Overall, super pleased