Huh, I haven't had that problem in about 7 years of using a custom domain name. Maybe the distinction is that mine is a .com? I feel like enough businesses themselves use custom domain names that dropping unknown .coms would break a ton of legitimate B2B traffic, but perhaps .me less so.

How did you notice this?

I use a .me domain myself but I haven't had any spam problems. Although I share it very very sparingly and have a catchall on another domain that I use for signing up with any service / sharing with non-trusted contacts. Even there, the spam problem isn't bothersome.

Make sure you setup SPF/DKIM/DMARC and you should be fine 99% of the time.

- Disclosure, I work for dmarcian

Which FastMail does if you have them host your DNS!

Fast mail will host your DNS? Had not seen that...

Don't use any of the "unsual" TLDs, like .io, .me, .toys, etc.

Surprisingly difficult for a personal-professional email if you have a somewhat common name. Nearly everything under the main TLDs was bought up ages ago. The issue can be mitigated with some creative branding work, but that’s arguably not any easier.

I've used .io and other "unusual" TLDs for a while and never had an email bounce or flagged as spam.

As someone else pointed out, make sure you setup spf, dkim, and all the other jazz. Some providers will host and setup the dns for you but its always best to use your own dns provider as the records are relatively easy to setup.

I haven't had any issues with my personal domain in years, ever since I moved it from random web host to GApps, to deal with IP reputation issues, and have SPF+DKIM setup. (but my domain is a .net one)

Did you manage to configure SPF correctly in your DNS records?