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Re:UBiome received $83M in Series C financing by refurb on Friday September 21, 2018 @04:19PM (#18042377)
Fecal transplants are not new science and C. Difficle is just a bacterial infection. The relationship to microbiome science is minimal.

As for the science around the microbiome role in metabolic, developmental and autoimmune disorder is observatory at best. I’ve yet to see a paper that took a human, changed their microbiome and observed X effect (beyond the obvious bacterial infection example).

Re:UBiome received $83M in Series C financing by armedgorillas on Friday September 21, 2018 @05:07PM (#18042657)
I'm not quite following how the relationship between microbiome science and an infection of the microbiome is minimal.

But more to your point, using the mg data from their "healthy" population along with the open-label data in the literature seems like a good way to construct RCTs, no? Data from open label studies isn't speculative... it's just not phase 3.

In case you're curious, here are two papers on UC: https://www.ncbi.nlm.nih.gov/pubmed/28214091 and https://www.ncbi.nlm.nih.gov/pubmed/29052237