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Re:GlaxoSmithKline makes $300M investment in 23andMe, forms ... by ig1 on Thursday July 26, 2018 @07:27AM (#17616568)
Those aren't false positives in that they represent real genetic relationships (i.e they're identical by descent), as the database size increases you don't increase the false positive rate in any meaningful sense at higher match levels.

If you've got a identical twin then you're right that their child will be genetically indistinguishable from your child. But that's down to the nature of genetics rather than anything to do with the reliability of testing or database size.

Re:GlaxoSmithKline makes $300M investment in 23andMe, forms ... by Retric on Thursday July 26, 2018 @09:53AM (#17617491)
False positives don't necessarily mean the test was executed incorrectly. It often means you are testing for something closely related to the information you want.

If a test failed because _ then it failed independent of why it failed. If your long lost twin causes you to be involved with a paternity suit or homicide investigation then that's both a false positive and a significant problem.