i'm of the opinion that the psychotic breaks risk would be an engineering problem to overcome in the context of using psychedelics therapeutically.

besides, in a clinical context, it's highly unlikely any kind of psychotic break could get too far out of hand; an astute clinician would recognize the patient spiraling out of their control and administer a correcting dose of an anxiolytic, or, failing that, a trip-ender like an antipsychotic.