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Re:Psychedelics could heal brain cells in people suffering f... by cyberpip on Tuesday June 12, 2018 @02:34PM (#17296422)
Lately, all this media attention to psychedelics reminds me of this Terence McKenna quote:

"[W]hy this[psychedelics] is not four-inch headlines on every newspaper on the planet I cannot understand because I don’t know what news you were waiting for, but this is the news that I was waiting for. It’s an incredible challenge to human understanding to try and make sense of this."

from https://www.asktmk.com/talks/Rap+Dancing+Into+the+Third+Mill...

https://youtu.be/adDRsqEj4PU?t=1641

Re:Psychedelics could heal brain cells in people suffering f... by pmoriarty on Tuesday June 12, 2018 @03:11PM (#17296866)
"[W]hy this[psychedelics] is not four-inch headlines on every newspaper on the planet"

Psychedelics might reveal to you that the neat little reality that you thought you had all figured out is a lot stranger and different from from what you thought it was, that your understanding of it might be all wrong, and that your place in it might not be all that cozy and secure. The experience could put everything in to question for you.

A lot of people feel threatened by that, so they try to push it away, lock it up, turn it off, or dismiss it.

Contrast that reaction to that in some other societies with a long tradition of psychedelic use. Psychedelic experiences there usually confirm the world view of the society, and tend to be very positive and accepted.

Re:Psychedelics could heal brain cells in people suffering f... by cyberpip on Tuesday June 12, 2018 @03:24PM (#17297028)
Another Terence McKenna quote I'm reminded of!

"The British enzymologist, J. B. S. Haldane in the 1920s, in an essay, said, "The universe may not only be stranger than we suppose; it may be stranger than we can suppose," and I suggest to you that as we look back over human history, every pinnacle of civilizationf whether it be Mayan or Greco-Roman or Song dynasty, has believed that it was in possession of an accurate description of the cosmos and of man's relationship to it. This seems to go- this seems to go along with the full flowering of a civilization. But, from the point of view of our present civilization, we regard all those conceptions as, at worst quaint, at best half right, and congratulate ourselves that our civilization, at last, has its finger on the real description of what is going on. " from https://www.asktmk.com/talks/Psychedelic+Society?query=stran...

Re:Psychedelics could heal brain cells in people suffering f... by yosito on Tuesday June 12, 2018 @11:23PM (#17299984)
Eh, I'm not saying we have a full picture of what's going on, but the scientific method is much more effective at helping us arrive at a real description of what is going on than any arbitrary religion of the past.
Re:Psychedelics could heal brain cells in people suffering f... by GuiA on Wednesday June 13, 2018 @01:37AM (#17300522)
The scientific method is the most important tool that humanity has ever developed, without question.

That being said, the belief that the scientific method can build up arbitrarily accurate models of any observable phenomena is without foundation, yet some behave as if it is obviously true.

Until we have something like a unified model of physics, there is no reason to believe that statement to be true.

(and in fact, the scientific method has led to results like Gödel’s incompleteness theorem, which makes it perhaps more likely for it to be false)

Re:Psychedelics could heal brain cells in people suffering f... by mythrwy on Wednesday June 13, 2018 @10:47PM (#17308873)
I question that the scientific method is the most important tool humanity has ever developed.

Maybe numbers and language (especially written) are more important. Oh ya, and fire.

But the scientific method is way up there in important, no argument there.

Re:Psychedelics could heal brain cells in people suffering f... by dalbasal on Wednesday June 13, 2018 @04:10AM (#17301228)
Mmm. I don't disagree, but I do think it's possible to overstate these things too. The scientific method is extremely effective at getting scientific answers to scientific questions.

Often though, we try to (or pretend we are applying this method to achieve unscientific questions (a la Karl Popper's criticisms of Scientism) or try to add up scientific answers in an unscientific way.

When we do that, we are using the (well earned and underappreciated) cultural authority of science in ways that do not promote truth seeking.

Re:Psychedelics could heal brain cells in people suffering f... by perfmode on Wednesday June 13, 2018 @12:09AM (#17300167)
So we believe, for now.
Re:Psychedelics could heal brain cells in people suffering f... by adrianN on Wednesday June 13, 2018 @03:13AM (#17300948)
Asimov wrote an essay to counter that point: https://chem.tufts.edu/answersinscience/relativityofwrong.ht...
Re:Psychedelics could heal brain cells in people suffering f... by maxerickson on Tuesday June 12, 2018 @09:34PM (#17299580)
None of the earlier ones had lasers though.
Re:Psychedelics could heal brain cells in people suffering f... by bernardino on Tuesday June 12, 2018 @06:43PM (#17298753)
> A lot of people feel threatened by that, so they try to push it away, lock it up, turn it off, or dismiss it.

You hit the nail right on the head.

It reminds me about how we want and need security, particularly around our beliefs. What I think is true in that regard is what Adyashanti, a spiritual teacher, once noted: "The magical part is that the more you let go, the better it feels. The more you step into insecurity, the more you notice how secure and safe it is. Where you just stepped out of was unsafe. Everyone is so miserable because they seek security in things that are limited and always moving and changing unpredictably."

Re:Psychedelics could heal brain cells in people suffering f... by taneq on Tuesday June 12, 2018 @09:28PM (#17299553)
I've always felt that this philosophy, and others like it, ultimately boil down to "you're going to lose no matter what, so try not to care about the game."
Re:Psychedelics could heal brain cells in people suffering f... by b6 on Wednesday June 13, 2018 @01:42AM (#17300542)
That's really not it at all. Have you heard the story "who knows what's good or bad"?

Something happens, and we judge it good and feel good about it. Then something else happens, and we judge it bad and feel bad about it. And so on. Our feelings are put on a roller coaster according to our judgements. But we don't have enough information to judge anything good or bad. It always remains to be seen. Deeply internalizing this results in equanimity.

Re:Psychedelics could heal brain cells in people suffering f... by taneq on Wednesday June 13, 2018 @02:40AM (#17300796)
There are plenty of things that are pretty unequivocally good or bad. When we anticipate one of these things happening, our emotions change accordingly and this helps to guide our actions in avoiding or encouraging the thing in question. That's what emotions are for. If you have any control over the course of events that affect you, you should experience an emotional response. Anything else just seems like learned helplessness.
Re:Psychedelics could heal brain cells in people suffering f... by b6 on Wednesday June 13, 2018 @04:26AM (#17301288)
> There are plenty of things that are pretty unequivocally good or bad.

Could you name one? For maximum utility in this conversation, can you pick something likely to happen more than once in an ordinary life, some common case?

Re:Psychedelics could heal brain cells in people suffering f... by chongli on Wednesday June 13, 2018 @08:03AM (#17302263)
I am not the GP but I will give it a try. Unequivocally bad:

Death of a loved one.

Unequivocally good:

Birth of a child.

Most people tend to experience these things more than once in a normal life. They represent a reality more real and more final than even psychedelics could manage: life and death. Impermanence.

Re:Psychedelics could heal brain cells in people suffering f... by b6 on Wednesday June 13, 2018 @10:20AM (#17303288)
> Unequivocally bad: Death of a loved one.

Imagine how it would be if we didn't die. So is death good or bad?

I have a family friend whose first wife died of cancer. After mourning for years, he found another woman and married her. Unlike his first wife, she was insistent on having a baby. When their baby was born, he told us that, having held his child in his arms, he understood now that it would have been a huge mistake not to have had a child as he originally planned with his first wife. So was the death of his loved one good or bad?

> Unequivocally good: Birth of a child.

My sister was born and it must have been a very happy event. When she died it was very hard for my parents. Was her birth good or bad?

This is what the story is getting at. It doesn't make sense to assign good or bad to things. We don't have enough information yet. And we never do. It perpetually remains to be seen.

It's not apathy or learned powerlessness to accept the fact of reality that you just don't know enough to say whether something is good or bad. It's wisdom.

Re:Psychedelics could heal brain cells in people suffering f... by taneq on Wednesday June 13, 2018 @10:12PM (#17308714)
You're being obtuse. If losing a loved one before their time isn't "bad" then your definition of the word "bad" is useless, or at least irrelevant to our current discussion.
Re:Psychedelics could heal brain cells in people suffering f... by b6 on Wednesday June 13, 2018 @11:09PM (#17308956)
What is "their time"? Do you know the correct time for each person to die?
Re:Psychedelics could heal brain cells in people suffering f... by vidarh on Wednesday June 13, 2018 @03:16AM (#17300972)
It's closer to 'try not to be attached to specific outcomes'. It's fine to play the game, as long as you don't get so hung up on trying to 'win' that you can't enjoy your life along the way. It's highly unlikely that you'll get to a point where you think that now you've won and can just enjoy, so focusing too much on the game means you will eventually lose - you're not going to live forever. The 'wins' are happening along the way, and if you look, you'll find many of them at times when you're 'losing'.
Re:Psychedelics could heal brain cells in people suffering f... by bencollier49 on Wednesday June 13, 2018 @04:23AM (#17301277)
Unfortunately, certain psychedelics have the effect of imbuing everything with significance, which results in apparently "earth shattering" revelations during an experience which later turn out to be dross. Unfortunately in some cases people carry on believing the dross.

It's like hearing a song or a joke in a dream which seems really beautiful or funny, and turns out to be utterly dull when you wake up and replay it.

So sure, altered perceptions give the lie to some of our assumptions about the world, and can lead to some interesting insights, but they also add a lot of new assumptions which are not healthy, and certainly aren't adapted to functional life in the non-psychedelic world.

Re:Psychedelics could heal brain cells in people suffering f... by cyberpip on Wednesday June 13, 2018 @10:17AM (#17303262)
I'd agree that it does make everything seem significant, at least for a period, but it's what comes after that has significance, after a period of integration. It creates an ability or a moment to come at a problem from a new angle, previously closed off to a person due to their established thinking patterns and past experiences. I think the important thing to consider here is that if a person goes into these experiences with a goal, it's likely they will gain new insight on that goal, at least from my experiences.

Curious though, what kind of new assumptions do you consider unhealthy?

Re:Psychedelics could heal brain cells in people suffering f... by bencollier49 on Wednesday June 13, 2018 @11:18AM (#17303885)
I'd say persistent relations between unrelated ideas, magical thinking and schizotypal behaviour. Also potentially, fixation on "new perspectives" which might not actually be optimal.

That said, I largely agree with your perspective as well: "The opposite is also true".

Re:Psychedelics could heal brain cells in people suffering f... by Ntrails on Wednesday June 13, 2018 @04:03AM (#17301197)
> Psychedelics might reveal to you that the neat little reality that you thought you had all figured out is a lot stranger and different from from what you thought it was, that your understanding of it might be all wrong, and that your place in it might not be all that cozy and secure.

Distorting perception doesn't reveal truth, it simply allows you to experience something "other" than reality. It's not that this is bad, but I don't accept that it offers enlightenment or wisdom.

Re:Psychedelics could heal brain cells in people suffering f... by cyberpip on Wednesday June 13, 2018 @10:21AM (#17303292)
I'd argue that it allows you to experience a _different_ reality, which, when juxtaposed against the collectively agreed upon reality we all live in, offers insights. Though I'd be skeptical of anyone claiming enlightenment, I do believe some wisdom is possible, if not just very useful insight.
Re:Psychedelics could heal brain cells in people suffering f... by Ntrails on Wednesday June 13, 2018 @11:16AM (#17303871)
I'd need some argument for it being a different reality.

Brain in a jar/The matrix style VR perception altering technology could make me experience a different world - but it wouldn't be reality. I actually could still see this resulting in wisdom under certain circumstances, so I guess I have to cede that actually :)

Re:Psychedelics could heal brain cells in people suffering f... by taurath on Wednesday June 13, 2018 @03:46PM (#17306339)
> "Psychedelics might reveal to you that the neat little reality that you thought you had all figured out is a lot stranger and different from from what you thought it was"

Or for people that are severely depressed, that your broken reality and thought loops that are deeply ingrained can actually be healed without a major neuronal shift.

Re:Psychedelics could heal brain cells in people suffering f... by psyc on Tuesday June 12, 2018 @09:03PM (#17299436)
Psychedelics punch through the big illusion, as in maya. They give the game away. I feel people are subconsciously and collectively terrified of this.
Re:Psychedelics could heal brain cells in people suffering f... by dagaci on Wednesday June 13, 2018 @04:03AM (#17301200)
The sudden lift of mood engendered by drugs should imprint the idea that "the depressive cycle can be easily dismissed and is not useful in anyway" when as you unwind, recalling that experience is a key to permanently removing negative cycles without drugs.
Re:Psychedelics could heal brain cells in people suffering f... by cyberpip on Wednesday June 13, 2018 @10:22AM (#17303298)
I completely agree. Once you know that you can break free from a mental pattern, the trick to getting yourself out of it in the future seems easier. Once shown, you learn.
Re:Psychedelics could heal brain cells in people suffering f... by s-shellfish on Tuesday June 12, 2018 @09:32PM (#17299568)
Is it at all possible to explain this to a sober person? One who is neither consciously nor subconsciously afraid of having the illusion removed?
Re:Psychedelics could heal brain cells in people suffering f... by wahern on Tuesday June 12, 2018 @10:17PM (#17299745)
It's no more possible to do that than for a schizophrenic to explain his delusion.

The difference between a psychedelic experience and mental delusion is that the former brings a newly found perspective on and (knowingly or unknowingly) appreciation for the "big illusion". The latter usually reflects a degenerative condition and the delusion may never end.

Both no doubt lead to fascinating experiences but they're intrinsically non-sense. There are tantalizing connections to be made that are _just_ out of grasp, and always will be.

As a child I once had a fever so high that Lego blocks began to fall from the ceiling and stack up around my bed. I ran out of the room before I could be crushed. Also as I child I learned how to lucid dream; only marginally less non-sensical, though at least there's the interplay between conscious thinking and the dream world. I've also befriend a few far-gone schizophrenics over the years; quite fascinating but, again, it's pointless to try to unpack the delusion. For me these personal and recounted experiences _reinforce_ my appreciation for the "big illusion".

What bothers me about people who promote psychedelics is that they ignore the utter fragility of the human mind. Most people will come back from their experience but in others it can instigate or hasten mental decline (e.g. schizophrenia, psychological dependency). That may or may not have happened regardless, but if you want to promote self-knowledge, IMO the most important thing to _know_ is how precious and fragile the "big illusion" is, and maybe lead with that.

It's sort of like promoting fasting by exclaiming that hunger is awesome. I don't think starving people think hunger is awesome. Fasting isn't a way to learn that hunger is an illusion; it's a way to appreciate what you have and your relationship to it. (I've also experimented with fasting.)

I've never taken psychedelics and wouldn't do it recreationally because, frankly, I'm too scared. And it's unnecessary. More power to people who do but it'd be nice if they were less flippant about it.

Re:Psychedelics could heal brain cells in people suffering f... by acjohnson55 on Wednesday June 13, 2018 @03:23AM (#17301008)
> What bothers me about people who promote psychedelics is that they ignore the utter fragility of the human mind. Most people will come back from their experience but in others it can instigate or hasten mental decline (e.g. schizophrenia, psychological dependency).

I am apparently very sensitive to THC, because under what seem like mild doses to most people, I feel like I have lost my grip on reality in a deeply uncomfortable way. I have never tried more serious psychedelics due to fear for my safety and sanity.

I suspect many people have experiences that feel much more manageable. But I agree with your skepticism about the maximalist viewpoint.

Re:Psychedelics could heal brain cells in people suffering f... by drvdevd on Tuesday June 12, 2018 @11:12PM (#17299951)
Psychedelics produce their effects by modulating certain receptors in the brain and body so as to alter perception until they are broken down through metabolism.

We don’t yet fully understand exactly how these alterations work objectively. But they do suggest that our subjective constructions of reality are just that: constructions.

So the only illusion to lose is the entire nature of reality: in some sense there is more than one “reality”, as far as your brain is concerned.

I think this is the sober, science backed version of this notion and I think it is profound.

Re:Psychedelics could heal brain cells in people suffering f... by tpm on Wednesday June 13, 2018 @05:49AM (#17301666)
It is possible to explain this on a few different levels. Though obviously it will make more sense when you actually experience it.

For example, if you imagine the brain as a big Bayesian classifier, which is filtering and shaping the inputs through the prior "knowledge", then the psychedelics block the prior and let you experience the inputs in a different way from your sober, usual, daily experience. Now they don't completely block all the priors all the time, so you can consciously understand what's happening. Also, "inputs" don't come exclusively from the external world, they can be your thoughts, memories and so on. And without the priors blocking and shaping them, they re-surface (which is the basis of the name psychedelia) and show themselves in a new light. So you can process them again, in a better way, for example.

Re:Psychedelics could heal brain cells in people suffering f... by yosito on Tuesday June 12, 2018 @11:28PM (#17300004)
Sure. And it's also possible to explain to a homebody who is not afraid of traveling what another country is like, but nothing can replace going there first hand and experiencing life in that place.
Re:Psychedelics could heal brain cells in people suffering f... by gepi79 on Wednesday June 13, 2018 @03:38AM (#17301075)
Do not fall for the romantic tales of psychonauts to reach some kind of enlightenment. All these people suffer from psychosis.

The human experience of the world (thoughts, vision, audition, pleasure, fear,...) is triggered by the nervous system (including the brain) that reacts on bio-chemistry.

Changing the bio-chemistry changes the human experience but gives no super powers. Most likely your thoughts on drugs are less smart but appear smart to you. Similar to other drug intoxications that disturb the normal brain activity and the sober judgement of your thoughts and experience of reality.

Granted, some people have been able to solve some of their problems with psychedelics because they are strong destabilizers.

https://www.rollingstone.com/culture/features/how-doctors-tr...

I am in favor of using psychedelics as last resort medicine under supervision of a medical expert.

But I am against the promotions of psychedelics by people who are either lucky (no bad life changing effects for months or years because of drug induced trauma with PTSD or bad neuroplasticity) or suffer already from psychosis.

Re:Psychedelics could heal brain cells in people suffering f... by simplemts on Wednesday June 13, 2018 @03:54AM (#17301151)
"Do not fall for the romantic tales of psychonauts to reach some kind of enlightenment. All these people suffer from psychosis."

Nothing like a blanket statement in your first sentence to immediately discredit your argument.

"All black people... All psychonauts... All Americans..." When you look at it yourself... doesn't it sound stupid to try to argue this way?

There are now hundreds of studies showing numerous benefits to psychedelics, from anxiety, depression, OCD, anxiety, Autism, etc.

What more evidence and data do you need?

Re:Psychedelics could heal brain cells in people suffering f... by gepi79 on Wednesday June 13, 2018 @04:21AM (#17301267)
> "Nothing like a blanket statement in your first sentence to immediately discredit your argument."

My opinion is as valid as the opinion of psychonauts. Maybe more so because I do not rave about great insights about the universe or gods or aliens or chakra or kundalini or third eye or old souls; New Age stuff whose proponents are famous for the promotion of altered states (!) by meditation or yoga or drugs.

> "There are now hundreds of studies showing numerous benefits to psychedelics, from anxiety, depression, OCD, anxiety, Autism, etc.

> What more evidence and data do you need?"

All noteworthy (positive) studies are published by medical experts.

All medical experts warn against the casual use of psychedelics. They all promote a therapy that might include psychedelics under supervision of a medical expert.

Only people who suffer from psychosis defend their delusions as real and important.

http://slatestarcodex.com/2016/04/28/why-were-early-psychede...

http://www.taraspringett.com/kundalini/kundalini-psychosis/

https://www.livescience.com/16287-mushrooms-alter-personalit...

https://www.rollingstone.com/culture/features/how-doctors-tr...

What more evidence and data do you need?

Re:Psychedelics could heal brain cells in people suffering f... by grabeat on Wednesday June 13, 2018 @06:07PM (#17307411)
No chakras, gods or old souls are needed for you to agree to the statement that some aspects of reality are constructed by the human mind (cf. Kant). It explains, for instance, why you perceive what you're sitting on right now as a "chair" rather than the mere collection of atoms and molecules that it's actually made of. Nature outside of the mind has no concept of an object, and no concept of a subject. Acid may help one see reality that way, if one is curious and mentally stable enough to want to.

Disclaimer: NOT intended to be a substitute for professional medical advice, diagnosis, or treatment

Re:Psychedelics could heal brain cells in people suffering f... by CuriouslyC on Wednesday June 13, 2018 @10:39AM (#17303483)
You have no idea what you're talking about. The thing that makes psychedelics so good at curing depression is that they are able to consistently induce a new perspective in people that is much healthier than the one that results from all our modern "knowledge." It has nothing to do with random destabilization at all.
Re:Psychedelics could heal brain cells in people suffering f... by taneq on Tuesday June 12, 2018 @09:27PM (#17299551)
Well they should be. Lovecraft was right, human minds aren't well equipped to handle the true nature of the universe.