I'm really torn here. Do you use less code and support Safari and Chrome, or wait for jQuery Mobile, which has wider support. Anybody have thoughts to offer here?

I've already run into an issue in which somebody complained about Skyfire not working with something as simple as a click binding.

I'm waiting. Targeting Webkit is no better than targeting IE.

If you're developing for mobile and targeting WebKit you're targetting iPhone, Android, Palm, and (soon) Blackberry. Those are the major smartphone vendors.

You can add Symbian and Samsung/Bada too.

http://www.cloudfour.com/mobile-operating-systems-and-browse...

Regardless of its adoption, zepto.js shines by the beauty and brevity of its source code. Well done Thomas!

This sounds nice, but as a potential user of JavaScript frameworks, it is feeling like there are just way too many of them and they are undifferentiated enough that culling a set to evaluate is so difficult that i've just out it off for the most part... Or will simply default to whatever apple ships in their next major web product...

What other low-level mobile JS frameworks are there other than this and Xui?

There's baseJS http://paularmstrongdesigns.com/projects/basejs/