I mean, they're people. I'm still close friends with a few of them, and I didn't like some of them. It's no different than working with anybody with a disability or an illness (or kids, or elderly parents, or any of the million other human things that can make you a less-than-full-functionality worker bot) - you make the necessary accommodations, work around issues when they arise, and live with it. Specifically, it involved toning down a bro-y, combative work environment (which was a change that I really appreciated).

I worked with a guy who had pretty bad autism and social issues. He was a great guy to work with, incredibly smart and a really nice guy.

He wasn't going to come to any works nights out or even lunches and like you said certain accomodations have to be made, e.g. access to a private quiet room for him at certain times... Able to work from home when he had to etc.

His father had to go to his interview with him, luckily the company allowed this. We have since gone our seperate ways but wherever he is working now got a great developer. I'd happily work with him again.