I have gone back and forth with a lot of different tools from Django to Vert.x, React, Vue, etc etc. But these days my default stack is more and more to use Grails (because although ridiculously heavyweight it's the most feature complete yet self-contained full-stack framework for extremely rapid develoment) and VueJS (because it straddles well between light-weight, inject a component or two use case and the full on webpack build setup).