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Re:Making WebAssembly better for Rust and for all languages by pjmlp on Wednesday March 14, 2018 @06:26PM (#16588892)
Mesa in Xerox Star, TIMI in IBM i, Language Environment on IBM z, MCP in Unisys ClearPath, UCSD Machines are some of the most well known examples.

Using bytecode as portable executable format has been a tradition in mainframes since the early 60's.

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