That said, JACK is much better for routing audio through applications. And jack-rack actually lets you change the parameters of LADSPA filters without reloading. And it is easy to get a graphical mixer up controlling individually the volume from all the sources.
I stacked a number of filters on a null-sink and then used the loop-back module to put the sound from the mic into the top filter. Then I redirected mumble to the null-sink’s monitor. The filters I used were the ones I found in the debian package repo.
In comparison, it was much easier to do in JACK, where I could create the filter stack in jack-rack[1], which has a GUI, and do the plumbing in qjackctl.
[0] https://www.freedesktop.org/wiki/Software/PulseAudio/Documen...
Before PulseAudio came along, my "solution" to Linux desktop audio was to simply keep using an ancient sound card that still had a hardware mixer.