At some point though, you have to make a decision on what type of customer/client relationship you want. I'd wager in many cases you get more customers at a lower price point. If so, then it is more of a 1:many relationship. If you have significantly fewer, I consider them to be more like a "client" in the sense that you likely have a more personal relationship with them.

The way to develop and manage those relationships would likely be very different, and that has implications throughout a company including support, marketing, sales, etc.