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Re:Ask HN: I'm writing a book about white-collar drug use, i... by Eilene on Monday February 26, 2018 @10:55AM (#16466163)
Peter said he thought he needed modafinil. Why is it a hot topic now? His thought way back was that it was everything he needed at the time--mood regular, stimulant.
Re:Ask HN: I'm writing a book about white-collar drug use, i... by oil7abibi on Monday February 26, 2018 @11:06AM (#16466267)
It said to have characteristics of a holy grail stimulant: increased performance without the crash or heavy tolerance build.
Re:Ask HN: I'm writing a book about white-collar drug use, i... by ShabbosGoy on Monday February 26, 2018 @11:12AM (#16466313)
That’s an odd assertion to make when the full pharmacodynamics and mechanism of action are unknown. Modafinil doesn’t increase your cognitive performance in the way that a substituted phenethylamine would. Focus and attention are certainly related to wakefulness, but wakefulness in and of itself doesn’t increase cognitive performance.
Re:Ask HN: I'm writing a book about white-collar drug use, i... by Eilene on Monday February 26, 2018 @11:27AM (#16466456)
Can you tell me what substituted phenethylamine is?
Re:Ask HN: I'm writing a book about white-collar drug use, i... by TheAdamAndChe on Monday February 26, 2018 @11:37AM (#16466561)
Substituted phenethylamines[1] are derivative compounds of phenethylamine. Many substituted phenethylamines are stimulants, while some are psychedelic too. Dopamine, epinephrine, amphetamine, pseudoephedrine, MDMA, and many others are considered to be substitued phenethylamines.

[1] https://en.wikipedia.org/wiki/Substituted_phenethylamine

Re:Ask HN: I'm writing a book about white-collar drug use, i... by twi on Monday February 26, 2018 @11:49AM (#16466694)
No crash might be the problem with it: you try to go to sleep and end up just kind of laying there half the night.
Re:Ask HN: I'm writing a book about white-collar drug use, i... by ThrustVectoring on Monday February 26, 2018 @01:48PM (#16467836)
Modafinil interferes with sleeping less than other drugs - it's only a problem if you rely on the "crash" of running out of energy over the day to fall asleep.
Re:Ask HN: I'm writing a book about white-collar drug use, i... by cryoshon on Monday February 26, 2018 @11:46AM (#16466662)
it's heavily dependent on the right genetic makeup from what i know.

for some it provides clarity, for others, fog. the dopamine transporters are very mysterious to me.

Re:Ask HN: I'm writing a book about white-collar drug use, i... by Eilene on Monday February 26, 2018 @10:55AM (#16466165)
regulator, sorry.