Re:Ask HN: I'm writing a book about white-collar drug use, i...
by anonyx69 on Monday February 26, 2018 @10:52AM
(#16466137)
Modafinil is a hot topic these days
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Re:Ask HN: I'm writing a book about white-collar drug use, i...
by TheAdamAndChe on Monday February 26, 2018 @11:00AM
(#16466222)
Yup. I used adrafinil(prodrug of modafinil) regularly during university and found it particularly useful in my programming classes. It helped me get "in the zone" while avoiding the euphoria, BP issues, and recovery periods/withdrawals that stronger stuff does. Plus it doesn't show up in most drug tests.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by gwern on Tuesday February 27, 2018 @05:05PM
(#16478437)
When it comes to programming, I think I've found that modafinil (and doubly so for something which must be metabolized first) is not as helpful as I used to think it was. My problem tends to be getting started; but once I'm started, continuing is relatively easy. So for my purposes, a bit of nicotine gum is just as useful: cheaper & legal, doesn't last as obnoxiously long as -afinils do, and doesn't require as big or long-lasting dose. I've often wished for a modafinil which had a half-life of half an hour or an hour...
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by Eilene on Monday February 26, 2018 @11:04AM
(#16466253)
Do you still use that now? or other stimulants? Or did you find you didn't need it after college?
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by TheAdamAndChe on Monday February 26, 2018 @11:13AM
(#16466319)
I don't currently use it or other stimulants because I'm recently graduated, currently unemployed, and looking for work. Well I suppose I take caffeine, but I've mostly cycled off that too, and only take a single 200mg pill per day. If I get a job that requires a steady flow state or a high amount of productivity, I very likely will begin using it again.
I use it because I am not naturally suited for the work. I have a genetic variation(gs224) that makes me tired all of the time and stimulation-deprived. However in our current economy, it seems like the only career path I can take that will work with my abrasive, likely autistic personality while still providing long-term career growth opportunities.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by Eilene on Monday February 26, 2018 @11:28AM
(#16466464)
It sounds like you would need a stimulant of some sort, just to counter the genetic issue. Thanks for your candor.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by S_A_P on Monday February 26, 2018 @11:11AM
(#16466305)
I generally agree except that it seems to be a huge migraine trigger for me, so Ive stopped using it.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by sjtgraham on Monday February 26, 2018 @11:26AM
(#16466446)
In my experience that’s dehydration. Modafinil is a diuretic, and appetite suppressant. Not only are you taking on less water because you’re probably eating less but your body is expelling water at frightening rates.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by ThrustVectoring on Monday February 26, 2018 @01:50PM
(#16467849)
It's that or I think a lack of choline can also cause it. Cheapest and easiest solution is to eat some eggs.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by S_A_P on Monday February 26, 2018 @11:30AM
(#16466484)
That may be true to some degree, but I have also had them happen while purposely chugging water. My migraines are kind of cyclical as well. Could be coincidence.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by Eilene on Monday February 26, 2018 @10:55AM
(#16466163)
Peter said he thought he needed modafinil. Why is it a hot topic now? His thought way back was that it was everything he needed at the time--mood regular, stimulant.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by oil7abibi on Monday February 26, 2018 @11:06AM
(#16466267)
It said to have characteristics of a holy grail stimulant: increased performance without the crash or heavy tolerance build.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by ShabbosGoy on Monday February 26, 2018 @11:12AM
(#16466313)
That’s an odd assertion to make when the full pharmacodynamics and mechanism of action are unknown. Modafinil doesn’t increase your cognitive performance in the way that a substituted phenethylamine would. Focus and attention are certainly related to wakefulness, but wakefulness in and of itself doesn’t increase cognitive performance.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by Eilene on Monday February 26, 2018 @11:27AM
(#16466456)
Can you tell me what substituted phenethylamine is?
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by TheAdamAndChe on Monday February 26, 2018 @11:37AM
(#16466561)
Substituted phenethylamines[1] are derivative compounds of phenethylamine. Many substituted phenethylamines are stimulants, while some are psychedelic too. Dopamine, epinephrine, amphetamine, pseudoephedrine, MDMA, and many others are considered to be substitued phenethylamines.
[1] https://en.wikipedia.org/wiki/Substituted_phenethylamine
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by twi on Monday February 26, 2018 @11:49AM
(#16466694)
No crash might be the problem with it: you try to go to sleep and end up just kind of laying there half the night.
Re:Ask HN: I'm writing a book about white-collar drug use, i...
by ThrustVectoring on Monday February 26, 2018 @01:48PM
(#16467836)
Modafinil interferes with sleeping less than other drugs - it's only a problem if you rely on the "crash" of running out of energy over the day to fall asleep.