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Re:Why does drug resistance easily evolve but vaccine resist... by paviva on Sunday February 11, 2018 @02:38PM (#16354320)
As pointed out by IIIIIIIIIIIIIII, antibodies are way too massive and are not excreted in any significant amount (again, I am talking of normal physiology, not someone with very advanced kidney disease).

To give you an idea of the weight difference, an average human IgG[1] antibody is about 500 more massive than a pretty average small molecule antibiotic like levofloxacin[2]

[1]: https://en.wikipedia.org/wiki/Immunoglobulin_G

[2]: https://en.wikipedia.org/wiki/Levofloxacin

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