I've been eying Wire for the interface and ease of installation. In terms of looks and handling it seems like one of the best options to hand to people with little technical interest/aptitude/patience.

Moxie Marlinspike has commented that Wire does not use the Signal Protocol but only took some components from it and created their own protocol, which he did "not recommend" https://news.ycombinator.com/item?id=12690148 Has there been any changes to that situation?