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Re:Microsoft disables Spectre mitigations as Intel’s patches... by faragon on Monday January 29, 2018 @04:45AM (#16256479)
The main reason is that in Windows executable files and dynamic libraries (.exe and .dll) are locked while a process is using them, while in other systems, e.g. Linux, you can delete them from disk. The only absolute need for reboot should be an OS kernel update (there are cases where a kernel could be updated/patched without a reboot).

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