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Re:LuLu: An open-source macOS firewall that blocks unknown o... by eddieplan9 on Friday January 19, 2018 @05:37PM (#16190556)
Little Snitch has this with automatic profile switching: https://blog.obdev.at/automatic-profile-switching/ though you will have to build the list of rules yourself
Re:LuLu: An open-source macOS firewall that blocks unknown o... by j45 on Friday January 19, 2018 @09:27PM (#16191695)
With LS afaik it's not possible to run multiple profiles at the same time (say you have groups of rules for a particular app), otherwise it would be perfect.

ie., turn Apple Telemetry on or off.