Ask HN: What problems don't have a profitable business solution?

Re:Ask HN: What problems don't have a profitable business so... by chkte on Tuesday December 12, 2017 @06:55PM (#15910689)

My sister has a very serious, rare, disease. No companies have incentives to innovate in this field (pharma or whatever).

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Re:Ask HN: What problems don't have a profitable business so... by melling on Tuesday December 12, 2017 @07:22PM (#15910843)

There are lots of rare diseases that need someone to find funding and push the research.

Saw this one in the WSJ:

https://themighty.com/author/luke-rosen/

https://www.wsj.com/articles/on-the-way-to-a-rare-disease-cu...

And this one on ABC News tonight:

https://donate.curecmt4j.org/campaign/cure-cmt4j-advancing-g...

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Re:Ask HN: What problems don't have a profitable business so... by DoreenMichele on Tuesday December 12, 2017 @08:21PM (#15911209)

In the US, the FDA tries to incentivize it:

https://www.fda.gov/ForIndustry/DevelopingProductsforRareDis...

The problem is this results in drugs that cost a fortune and still only helps a small percentage of sufferers, like the $300k drug for CF that only helps 5% of CF patients.

http://www.cbc.ca/beta/news/canada/nova-scotia/cystic-fibros...

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