I did something like this in 2002 for a VFX house; but it was loading a DLL that hot loaded other DLLs, queried the routines and exposed them as Excel functions. Through that I pulled in a stochastic modeling framework I wrote, and pulled in 5 years of the studio's timecard records to create a production forecasting system, right down to selecting the correct staff for each position, with backup people, for 1200 digital artists. The Excel "spreadheet" was something like 250 MB when saved with a film production in it.