Amongst people who think this is reasonable are probably
- Dual earners hoping to bite the bullet before it gets crazier
- Those with <8yrs experience who have never seen a downturn or jobs go dry
- Lawyers, VCs, etc to whom this is nothing.
Law firm partners are in a much better position, but you can't make equity partner (not just "income partner", which is basically a glorified title they give so you can go get more clients) until you're about 40. And nobody wants to wait that long to buy a home.
Basically, "law firm partners" can be clumped together with VCs, since they both hold stakes in (hopefully) profitable businesses. But most lawyers are not partners.
It's also worth noting that these figures are for a mortgage, which is in part an investment. When the trend of SF area real estate is factored in, it doesn't look as crazy. If you purchase in very popular areas (Palo/Menlo/north MV, on the Peninsula), you're pretty well insulated from downside market risk. Even during the '08 recession, things mostly just flattened out for a couple years (and have since gone on a tear). People used to joke about million-dollar-fixer-uppers. Now even the fixer-uppers are well over a million...