This reminds me of an old (1928) piece titled "On Being The Right Size" by JBS Haldane [0], which lightly touches on many different concerns related to sizing:

> Of course tall land animals have other difficulties. They have to pump their blood to greater heights than a man, and, therefore, require a larger blood pressure and tougher blood-vessels. A great many men die from burst arteries, greater for an elephant or a giraffe.

https://irl.cs.ucla.edu/papers/right-size.html