Those 122 compounds were also over-representing publicly available products, as opposed to medically regulated compounds. You would need more rigor for a study where the compound efficacy actually mattered to make a general finding, across all classes of drugs. 25% difference in a beta blocker, glycerine, or blood thinner is a fatal change. These drugs are monitored with physical symptoms (metroprolol) and/or regular blood testing (sodium warafin/heparin/lovenox).