Well, yes, that's the goal. But it's surprisingly easy to mess up. I think the people here are cautioning you not to get overconfident, and to make sure you research the details of the flaws in other systems.

It is easy to mess up, yes. I'm not overconfident, but almost the opposite. Without being totally paranoid, I'm usually pretty certain something important is forgotten. All help is welcome :)

chromeIPass' possible vulnerabilities being?

KeePassXC restricts chromeIPass to localhost, so data should be safe. Still, chromeIPass exchanges encryption keys in base64. Basically that's plain text. These are the only keys used, so technically it's possible to steal those keys (if not localhost). But if someone has permission to read your loopback or local packet traffic, your info is gone..

Other than that, chromeIPass uses quite old libraries and depricated API functions. Those haven't been updated in ages. keepassxc-browser should fix all issues mentioned above :)

Also, any autofilling is disabled by default.