Re:Ohio Sues 5 Major Drug Companies For 'Fueling Opioid Epid...
by IAmGraydon on Wednesday May 31, 2017 @07:56PM
(#14456854)
With all due respect, dosing schedule and biological half life have little to do with the addictive potential of oxycodone. Put simply, it lights up the brain's reward center like a Christmas tree. If you dig, you can find studies that show that oxycodone causes a far greater dopamine release in the nucleus accumbens than even IV heroin. This has been known for a long time. The people who developed oxycodone knew what they were doing - engineering the most addictive opiate on the market. Purdue really needs to be held accountable for what they've done and the lives they've ruined and/or ended. The blame for the opioid epidemic falls squarely on them, in my opinion.
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Re:Ohio Sues 5 Major Drug Companies For 'Fueling Opioid Epid...
by SmellTheGlove on Wednesday May 31, 2017 @10:40PM
(#14457584)
It's scary good. I've had it prescribed to me twice - once when I had my wisdom teeth out (a fairly significant surgery, they were bony impacted) and again when I had a hernia repaired. Both were 5mg, 30 pills. I took 'em all. This was years ago, but I still remember to this day _exactly_ how good they made me feel. Scary stuff, I'll never fill a prescription for these again, I don't give a shit what I have going on.