http://blogs.sciencemag.org/pipeline/archives/2012/03/08/ero...
And, well, medicine ain't all it's cracked up to be:
https://ello.co/dredmorbius/post/msqfdpan_0xudzuorebfbg
Which is to say, you're vastly better off investing in public health measures than in intensive medical interventions.
(See Laurie Garrett, The Coming Plague, for more on that theme.)
I think we can all agree that drug patents in particular are a necessary evil. On other patents (in particular software) I'm a lot more skeptical. And that's not to say "Big Pharma" isn't trying to abuse the system to maximise their profits.
I could imagine some models to make them less evil, for example by having a scheme that forces companies to grant fairly priced licenses to their competitors. Or, for drugs whose availability is in society's general interest, a government reimbursing the development costs. For both of these one would need a fair way of determining development costs, but as far as I understand pharma research already has a detailed paper trail to make sure their patent applications are bullet-proof.
> * EpiPen pricing
My understanding was that part of the problem with the EpiPen was a monopoly due to patent issues. Patents are monopolies created by the government, so the market failures they cause are in fact government failures.