It would be nice to see Nvidia or someone expand on this, so that users who have to make this choice can do so without guessing. If Google or AWS or M$ could publish reliability information, that'd be cool too.

Illustrative case: I run Monte Carlo work on GPUs and administer a local compute cluster. I tested a workload on a 16 GB P100 and a GTX 1080. A 12 GB P100 costs (academic, EU) 5000 euros while the latter costs 700 euros, but the performance difference is about 2x. Still, when we ask Nvidia reps, they say not to bother installing GTX cards in our cluster, because they aren't designed for 24/7 work, not commercializable etc. Even so, the GTX would have to burn out 3 times before the choice of P100 breaks even. Burning out three times means GTX 1080, then 1180, 1280 etc.