The tradeoff in the current doctor's opinion is that taking them out nightly reduces infection risk theoretically, through nightly disinfection, better access to the eye surface for your immune system, and lower risk of corneal abrasions. But handling the contacts daily for removal/reinsertion provides a new route for infection, as a lot of infections are introduced by fingers, lens cases, etc. So the added handling might offset the benefits of nightly removal enough to make it a net loss, if you're one of the people for whom sleeping in contacts doesn't produce dry eyes or irritation. Real-world data seems not good enough to compare the magnitude of those two effects.
Supposedly if they continue to grow I could lose my eyesight, and they won't actually go away even if I stopped wearing lenses.
A coworker came into work one day with a really ugly looking right eye (red, tearing, etc.) Turns out he got whacked in the face by a tree branch on his way in (he rode his bicycle to work). He was even wearing glasses but apparently that didn't protect his eye (enough). He lasted about an hour before he left to go see his eye doc who diagnosed him with a corneal abrasion. Guy was in pain for weeks.
So my assessment is that corenal abrasions are caused by 'bad luck.'