Makes code more difficult to read. I consider this a language design error. I had that on the Lisp Machine 30 years ago (example callable arrays, ... - maybe even Maclisp in the 70s had it), few people used it and it did not make it into Common Lisp.
Common Lisp was designed such that for the programmer and for the compiler the first element of a Lisp form is easily recognisable as a function: it has to be a symbol naming a function or an actual lambda expression.
Pays back it code maintenance over time...
> but generally reads cleaner in the same way one might say a font reads cleaner.
I think it reads cleaner in the way PERL code is read cleaner.
Seq's as functions are sometimes more readable to me for the same reasons code that uses reader macros may be more readable to me (even though reader macros may do away with normal s-expression syntax entirely). But again, mileage varies.
There are some Lispy things that Clojure does out of the box that are more Lispy than than Common Lisp does out of the box, e.g. lists and other seq's as functions in the function position of an x-expression. There are things Clojure will not do such as reader macros. Clojure's syntax is a bit different, but generally reads cleaner in the same way one might say a font reads cleaner. YMMV.