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Re:Seagate Announces 12 TB HDD: 2nd-Gen Helium-Filled HDD by Dylan16807 on Thursday March 16, 2017 @10:11PM (#13890816)
Raid 10 still leaves you vulnerable to a second drive failure. I'd personally jump from a multiple parity scheme to at least raid 5+1 without ever stopping at 1+0.

(Though probably something with checksums instead of naked redundancy.)

Re:Seagate Announces 12 TB HDD: 2nd-Gen Helium-Filled HDD by myrandomcomment on Thursday March 16, 2017 @10:23PM (#13890869)
Using FreeNAS I have 4x4TB drives. 2 mirror sets that are mirrors of each other. Only 7.25TB total space but I am not to worried about a failure. Disk are cheap, loosing 16 years of family photos, not so much.