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Re:Revisiting 64-bit-ness in Visual Studio and elsewhere (2015) by syncsynchalt on Friday March 10, 2017 @02:47PM (#13841485)
It's not exactly what you're asking for, but you'll run into a big one in about two decades.

The only other example I can think of is the general "problem" of large databases. There's just a lot more paging and churn that has to happen in a 32-bit address space. Many NoSQL databases in particular have a memory model of mmap'ing an entire database, which runs into a hard limit on 32-bit address space.

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