People can handle some pain, and that is fine. 100% pain relief through opiates vs 50% pain relief through less detrimental means is probably worth it.
Although, I suppose the side effects of pot are considered desirable by many.
What are those? Beyond the physical addiction, which shouldn't be much of an issue with proper dosage.
But for the pure side effects, the most common issues are constipation and nausea. Then there's sedation (which may be comparable to effects of pot), and of course the suppressed breathing which makes accidental overdoses potentially deadly, unlike pot. Especially for chronic pain management, the long term effects add up, then you also risk liver damage, etc.
https://www.ncbi.nlm.nih.gov/pubmed/18443635 is a good place to start if you're interested in details.