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Re:React Native at Instagram by habosa on Monday February 06, 2017 @05:25PM (#13584861)
Almost every Android app that includes the most common dependencies (Android support lib, Google Play services, etc) will end up being multi-dex.

This used to be a massive pain but lately the Android Studio / gradle multidex tooling has gotten so good that I don't notice anymore.

Re:React Native at Instagram by krschultz on Monday February 06, 2017 @06:19PM (#13585278)
You still incur a startup penalty with multi-dex, it takes noticeably longer than a single dex, even if you are only marginally into that 2nd dex.