Most of the raised in the accepted answer to that SO question can in fact be applied equally well to div/css layouts as they're practiced in the wild. CSS Zen Garden is awesome and all, but I'm yet to see a fronted professional who does things that way.

For instance, arguments about ease of change (single place to modify) are irrelevant, because in both cases the single place to modify is the code that renders the layout.

Also, personally I'm not buying the whole separation of layout from content thing. It's an implicitly understood fact people seem reluctant to admit out loud: form is a part of content too! These are not orthogonal things.