There's been plenty of valid criticism directed at Guy here at news.yc (for example, he gives startup advice but hasn't had a successful startup of his own), but I really don't think he has a large ego. In fact, what I like most about his presentations, interviews, and moderatorships is that he's always poking fun at himself. He always mentions his stupid mistakes in a way that's funny and endearing.

I've also emailed him personally a couple times and he answered the email himself, which is not a characteristic of someone with a delusional sense of his own importance.