I do it from time to time - and I like it. Works well for small functions/procedures.

But try to use python beyond the pythonic way on a large scale and your in for a design challenge. But Im sure it'll be beautiful and you'll get much hate, as well as praise for it, heh.

Usually though, when I write python, I keep it pythonic, mainly for the support and debugging efforts.

The community's large code Base is pythonic and is designed to stitch together pythonically. Aslong as the API is pythonic, what lies underneath can be functional.