Also, the concept of IF being a proxy for rigorous review and work quality is weak at best. Just read a few pages of http://retractionwatch.com/
Particularly for early career people, I suspect most of these "quantitative" measurements are basically reflecting where and wtih whom you worked.
They used to have this nice trick where you hired the son of your friend and your friend hired your son. But at least now there are some non-subjective requirements to be met before anyone can get admitted.
(Disclaimer: I used to work in this field at biomedcentral.com)
Competition for positions in academia has gotten so bad that it doesn't matter. Like Google rejecting perfectly good candidates just because they can, but in Academia even south central Kansastucky state university has enough excellent applicants that arbitrary metrics do more good than harm.
In other words, I doubt anyone is explicitly penalized for submitting to PLoS Biology instead of Journal of Neuroscience. However, there is an implicit penalty for not submitting to Nature/Science/Cell.
[As an aside, I really hate the obsession with IF and all these other "quantitative" measures of research quality. They're all incredibly ad-hoc, someone easily game-able, and yet otherwise-smart people take them so seriously.]