Maybe, but clearly the net effect is positive, because unemployment has fallen by half since 2010, and is in fact currently below NAIRU levels[0]. So every job that has been lost has been replaced by more than one, on average.
(Before someone says "yes, but that's because the labor force participation rate has fallen" - that's another common remark that misses the point altogether. The economy has expanded during this timeframe, and while labor participation is a secondary concern, it's not a proximate one. If people are able to afford the choice not to work during a period of time in which the economy has expanded, that's unambiguously a good thing, even if it's not always the best case. Increasing participation in the labor force is often a goal, but not in and of its own sake. Unlike controlling excess unemployment or preventing GDP contraction, which are basically always bad, a drop in labor force participation is a more ambiguous signal of economic health).
[0] In other words, one could actually make the argument that unemployment is currently too low - although this would be a bit of a moot point, as it's still within measurement error of the NAIRU and has been for the last 13 months.
Wow, seems like worse news to me. The number of self-driving trucks on the road today is probably low to zero, but the number of non-grocery retail stores closing every year, largely due to competition from Amazon (but also stagnant wages keeping demand low), is clearly in the thousands. I don't think it would be crazy to predict closings and automation within the stores that remain (e.g. Amazon Go) driving a collapse in jobs over the next decade.
Some numbers on closings in 2016: http://www.clark.com/major-retailers-closing-stores