Bringing your laptop to meetings, or being able to remote in from home (taking it with you) are pretty huge benefits to usability. Though I do prefer a real (manual switch) keyboard, the touchpad on the mbp is awesome, and would actually be okay with that over a mouse.

Beyond that, the 16gb ram limitation is sometimes an irritation... All upgradability is locked out, which is sad. Prior to around 2011, I would always buy at the midrange and upgrade ram/hd a year in. I miss that option, but they want that extra $$$ from you.