Thanks for reaching out; will do if I encounter a case. I don't run Chrome daily, and my personal experience with Firefox is good, including with "big webapps" like Atlassian products (JIRA, Confluence), but I often read the comment that "big pages/webapps" are faster on Chrome than Firefox.
See https://news.ycombinator.com/item?id=12794971 for examples of such talk, but it's rarely precise enough to file a bug :/
If you have specific pages where you're seeing this, please file bugs on Firefox and add "bzbarsky" to the cc list for the bug!