Depends how much of your social life is tied to the evening and how much they expect you to be reachable. I worked for a Bay Area startup for two years from London. It was tiring at times, but I got into a habit of working a bit in the morning, taking a long break early afternoon and then working again late evenings, and it worked quite well, so it's possible.

Since the eastern US is only five hours behind London, you could have free time during the day and work mostly in the evening? Matinée prices, lunch specials, and most importantly sunlight abound! Right now I work for all of the good parts of the day and have free time during the bad parts.

(My data point is it's not a problem if your boss is hands off and your peers are hands on online)